With basic design parameters such as flow rate, rpm and head.
With a high level of accuracy. There's no need to run point-by-point computations.
Use Real Gas Applications with direct coupling to NIST REFPROP to create designs with new, low GWP refrigerants.
Use meanline solver coupled with automatic optimization to evaluate performances across all required operating points.
Coupled with compressor code to create single stage or 2 stage chillers, back-to-back or inline configuration.